MASKED

Motor Health and Semiotic Function in the Kinesthetic Expressivity of Neurodegenerative Disease
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MASKED is a transdisciplinary applied research project grounded in cutting-edge biosemiotics.

The aim is to address Parkinson’s disease (PD), its symptomatic hypomimia (“facial masking”), and the ever-increasing technological demand for early-indicating detection techniques. Through interdisciplinary, international, and intersectoral secondments, researchers train in world-leading measurement techniques, including the Facial Action Coding System (FACS) and the Neuropsychological Gesture Coding System (NEUROGES); cutting-edge measurement technologies; and advanced computational statistics analysis.

This novel advancement of applied semiotics harnesses objective, quantitative methods.

MASKED applies the statistical analysis of empirical laws to scientific measurements of nonverbal behavior. To generate statistical models and interpret semiotic meanings, the project considers the medico-scientific ethics and multi-perspectival values behind the hypomimic sign and its signification across environmental contexts and lived experiences. Both correlational methods and conceptual models play equally critical roles.

The principal objective is to develop innovative solutions for noninvasive symptom assessment.

These solutions will have not only long-term applicability across diagnostic, prognostic, and therapeutic disease stages, but also wide-reaching utility across provider, caregiver, and patient treatment stakeholders. The hope with the MASKED project is to improve patient-health outcomes and mitigate socio-economic burdens among families, communities, and societies affected by PD and related chronic, progressive illnesses.

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CONTACT
info@maskedhealth.org
10.3030/101236781
COORDINATION
Palacký University Olomouc
Křížkovského 511/8
779 00 Olomouc 9
Czech Republic
Data science, state-of-the-art training in manual and automated measurement, systems certification.
Data collection, online videos, data cleaning and preparation, training database.
Data exporting, behavioral annotation, intersystem comparison, trial and pilot studies.
Data analysis, expression dictionary, empirical laws, diagnostic index.
Data visualization, presentation and publication, next phases.

Open science

findable, accessible, interoperable, and reusable

MASKED aims to provide faster, more accurate diagnostics

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Patient-centered health solutions through the novel advancement of applied biosemiotics

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MASKED brings together both expert scientists and scholars based in Europe, North America, and around the globe.

The participating researchers in the MASKED project bridge the higher education sector and the medical technology sector. To enhance skills and foster collaboration toward achieving its objectives, they engage in interdisciplinary, international, and intersectoral secondments across the beneficiary organizations and the associated partners.
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Principal Countries

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Partner Institutions

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Participating Researchers

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Latest news

05 December 2025
MSCA-SE Official Kickoff
30 November 2025
Secondment: Olomouc
Duke Institute for Brain Sciences
Luminous
University of California, San Francisco, Department of Neurology
Erasmus University Rotterdam
Palacky University Olomouc
University of Florida
International Semiotics Institute
Sagewrite
University of Turin
International Association for Biosemiotic Studies
Toronto Metropolitan University
Webster Private University Vienna
This project is funded by the Horizon Europe / Marie Skłodowska-Curie Staff Exchange under Grant Agreement No. 101236781.
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